New heart valve implant aims to fix severe leak, improve lives

NCT ID NCT04482062

Summary

This trial is testing a new device called the Edwards EVOQUE system, which is implanted via a catheter to replace a leaky tricuspid heart valve. It aims to see if this implant, along with standard medication, is safer and more effective than medication alone for patients with severe valve leakage. The study will follow 864 participants for up to five years to measure improvements in heart function, quality of life, and walking ability.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ascension Via Christi St. Francis

    Wichita, Kansas, 67214, United States

  • Baylor Heart Hopsital Plano

    Plano, Texas, 75093, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Carolinas Medical Center

    Charlotte, North Carolina, 28203, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Columbia University Medical Center/NYPH

    New York, New York, 10032, United States

  • Emory University

    Atlanta, Georgia, 30308, United States

  • Florida Heart & Vascular Care - JFK

    Atlantis, Florida, 33462, United States

  • HCA Houston Healthcare

    Houston, Texas, 77004, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Herz- und Diabeteszentrum NRW, Bad Oeynhausen

    Bad Oeynhausen, 32545, Germany

  • Herzzentrum Dresden Universitätsklinik

    Dresden, 01307, Germany

  • Herzzentrum Leipzig GmbH

    Leipzig, 04289, Germany

  • Herzzentrum Universitätsklinik Bonn

    Bonn, 53105, Germany

  • Herzzentrum der Uniklinik Köln

    Cologne, 50937, Germany

  • Intermountain Medical Center

    Murray, Utah, 84107, United States

  • Johannes Gutenberg-Universität Mainz

    Mainz, 55131, Germany

  • Kaiser Permanente San Francisco

    San Francisco, California, 94118, United States

  • Kansas University Medical Center

    Kansas City, Kansas, 66160, United States

  • Klinikum der Universität München - Großhadern

    München, 81377, Germany

  • Lankenau Heart Institute

    Wynnewood, Pennsylvania, 19096, United States

  • Lenox Hill Hospital

    New York, New York, 10075, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical Center of the Rockies

    Loveland, Colorado, 80538, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • Morristown Medical Center

    Morristown, New Jersey, 07960, United States

  • NCH Heart Institute

    Naples, Florida, 34102, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • North Shore University Hospital

    Manhasset, New York, 11030, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Oklahoma Heart Institute

    Tulsa, Oklahoma, 74104, United States

  • Oregon Health & Science University

    Portland, Oregon, 97293, United States

  • Piedmont Heart Institute

    Atlanta, Georgia, 30309, United States

  • Rutgers Robert Wood Johnson Medical School

    New Brunswick, New Jersey, 08903, United States

  • SJHMC Heart and Vascular Institute

    Phoenix, Arizona, 85013, United States

  • Saint Luke's Hospital of Kansas City

    Kansas City, Missouri, 64111, United States

  • Saint Thomas Health

    Nashville, Tennessee, 37205, United States

  • Scripps Memorial Hospital La Jolla

    La Jolla, California, 92037, United States

  • Sentara Norfolk General Hospital

    Norfolk, Virginia, 23507, United States

  • St. Francis Hospital

    Roslyn, New York, 11576, United States

  • St. Vincent Heart Center of Indiana

    Indianapolis, Indiana, 46290, United States

  • Stanford University

    Stanford, California, 94305, United States

  • State University of New York at Buffalo

    Buffalo, New York, 14203, United States

  • Swedish Medical Center

    Seattle, Washington, 98122, United States

  • The Cardiac & Vascular Institute Research Foundation

    Gainesville, Florida, 32605, United States

  • The Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States

  • Tucson Medical Center

    Tucson, Arizona, 85712, United States

  • UC Davis Medical Center

    Sacramento, California, 95817, United States

  • University of California San Francisco

    San Francisco, California, 94143, United States

  • University of Maryland

    Baltimore, Maryland, 21201, United States

  • University of Michigan Hospital and Health Systems

    Ann Arbor, Michigan, 48109, United States

  • University of North Carolina - Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Virginia Mason Franciscan Health

    Seattle, Washington, 98101, United States

  • Weill Cornell Medicine-New York Presbyterian Hospital

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.