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New shot and infusion combo tackles tough blood cancer

NCT ID NCT06223516

Ongoing Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests an experimental drug called etentamig (ABBV-383) in about 55 adults with multiple myeloma that has returned or not responded to prior treatments. The drug is given as a shot under the skin or through an IV. The main goals are to check safety, side effects, and how the drug moves through the body. This is not a cure, but aims to control the cancer.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE MYELOMA

Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist Medical Center /ID# 260807

    Winston-Salem, North Carolina, 27157, United States

  • Hadassah Medical Center-Hebrew University /ID# 261446

    Jerusalem, Jerusalem, 91120, Israel

  • Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital /ID# 265286

    Nagoya, Aichi-ken, 466-8650, Japan

  • Kindai University Hospital /ID# 266016

    Sakai-shi, Osaka, 590-0197, Japan

  • Mayo Clinic - Rochester /ID# 262807

    Rochester, Minnesota, 55905-0001, United States

  • Mayo Clinic Arizona /ID# 260799

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Hospital Jacksonville /ID# 262808

    Jacksonville, Florida, 32224, United States

  • Sylvester Comprehensive Cancer Center /ID# 260798

    Miami, Florida, 33136-1002, United States

  • Tel Aviv Sourasky Medical Center /ID# 261525

    Tel Aviv, Tel Aviv, 6423906, Israel

  • The Chaim Sheba Medical Center /ID# 261699

    Ramat Gan, Tel Aviv, 5265601, Israel

  • Universitaetsklinikum Frankfurt /ID# 260442

    Frankfurt am Main, Hesse, 60590, Germany

  • Universitaetsklinikum Hamburg-Eppendorf /ID# 260444

    Hamburg, 20246, Germany

  • Universitaetsklinikum Koeln /ID# 260445

    Cologne, North Rhine-Westphalia, 50937, Germany

  • University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 261050

    Ann Arbor, Michigan, 48109, United States

  • Wisconsin Medical Center /ID# 261085

    Milwaukee, Wisconsin, 53226, United States

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