Can a single infusion or a crisis plan stop suicide? new trial aims to find out

This study tests two fast-acting approaches to prevent suicide in teens and adults who recently attempted suicide or have severe suicidal thoughts. One group receives a single intravenous dose of esketamine, another gets a one-on-one crisis planning session, and a third gets enhanced usual care. Researchers will track which approach best prevents future suicide attempts, hospitalizations, or deaths over one year. The trial takes place in public emergency rooms in Brazil and includes 468 participants.