Can a single infusion or a crisis plan stop suicide? new trial aims to find out
NCT ID NCT07120477
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tests two fast-acting approaches to prevent suicide in teens and adults who recently attempted suicide or have severe suicidal thoughts. One group receives a single intravenous dose of esketamine, another gets a one-on-one crisis planning session, and a third gets enhanced usual care. Researchers will track which approach best prevents future suicide attempts, hospitalizations, or deaths over one year. The trial takes place in public emergency rooms in Brazil and includes 468 participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Esketamine (intravenous infusion)
What this could lead to
If successful, this could provide a fast-acting, practical option to reduce suicide risk in public emergency settings, especially in low- and middle-income countries.
What could go wrong
This is a single infusion study; effects may be short-lived. The trial is not yet recruiting, and results may not generalize beyond the specific Brazilian public health context.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Prefeitura de Indaiatuba
RECRUITINGIndaiatuba, São Paulo, Brazil