Higher antidepressant dose may be risky for seniors with kidney disease
NCT ID NCT07274241
First seen Jan 03, 2026 · Last updated May 16, 2026 · Updated 20 times
Summary
This study looked at over 12,000 older adults (65+) with low kidney function to see if starting a higher dose (10 mg/day) of the antidepressant escitalopram is riskier than a lower dose (5 mg/day). The goal was to compare rates of hospitalization, emergency visits, or death within 30 days. The findings help guide safer prescribing for this vulnerable group.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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London Health Sciences Centre Research Institute
London, Ontario, Canada
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