New drug ERX-315 enters first human tests for tough cancers
NCT ID NCT06533332
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests the safety of a new drug called ERX-315 in 36 adults with advanced solid tumors (like breast, ovarian, or pancreatic cancer) that have stopped responding to standard treatments. Participants receive the drug intravenously twice a week at increasing doses. The main goal is to find a safe dose and check for side effects, not yet to prove it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ERX-315
- What this could lead to
- If it works, this could point toward a new treatment option for advanced solid tumors that no longer respond to standard therapies.
- What could go wrong
- This is a very early Phase 1 trial with only 36 participants, focused on safety and dosing. It is too soon to know if ERX-315 will be effective or have manageable side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Cancer Research SA
RECRUITINGAdelaide, South Australia, 5000, Australia
Contact Email: •••••@•••••
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Icon Cancer Centre Adelaide
RECRUITINGAdelaide, South Australia, 5037, Australia
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Macquarie University Health
RECRUITINGRyde, New South Wales, 2109, Australia
Contact Email: •••••@•••••
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The Kinghorn Cancer Center
RECRUITINGSydney, New South Wales, 2010, Australia
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Westmead Hospital
RECRUITINGWestmead, New South Wales, 2145, Australia
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