Could a simple exercise breathing test replace invasive heart probes?

NCT ID NCT04450459

Completed Diagnosis Sponsor: Jena University Hospital Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether a non-invasive exercise test that measures oxygen uptake (ergospirometry) can accurately detect heart ischemia in people with stable angina. Currently, the most reliable method is an invasive procedure called FFR, which measures blood flow during cardiac catheterization. The study compares the diagnostic accuracy of the ergospirometer test against FFR to see if it could serve as a better non-invasive alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ergospirometer test (a non-invasive exercise test that measures oxygen uptake and breathing during physical activity)
What this could lead to: If successful, this could provide a more accurate, non-invasive way to detect heart ischemia, potentially reducing the need for invasive procedures.
What could go wrong: The trial is relatively small and early-stage. The new test may not prove accurate enough to replace current methods, and individual results can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Angina, Stable

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STABLE ANGINA

Contacts and locations

Locations

Universityhospital

Jena, 07747, Germany

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