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Nerve block may help septic Patients' organs recover

NCT ID NCT05623722

Recruiting now Disease control Sponsor: Jing Cai, MD Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a nerve block (erector spinae plane block) can improve organ function in septic patients who also have acute gut injury. The block uses a numbing medicine (ropivacaine) delivered near the spine. Researchers will measure organ failure scores in 116 ICU adults over 7 days. If successful, it could become a supportive therapy for sepsis-related organ damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ropivacaine (a numbing medicine) given as a nerve block
What this could lead to
If it works, this could offer a new way to help septic patients with gut injury recover organ function faster in the ICU.
What could go wrong
This is a small, early-stage trial (116 people) and the nerve block is an add-on to standard care. The results may not apply to all sepsis patients, and there are risks like bleeding or infection from the procedure.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis multiple organ dysfunction syndrome Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE GASTROINTESTINAL INJURY ORGAN DYSFUNCTION SYNDROME SEPSIS

Contacts and locations

Locations

  • Department of Intensive Care Medicine of Zhujiang Hospital,Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, 510282, China

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