New pain block could cut opioid use after mastectomy

NCT ID NCT07562945

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a continuous nerve block using the numbing drug ropivacaine can reduce pain, inflammation, and opioid use in women undergoing mastectomy for breast cancer. Forty women will be randomly assigned to receive the nerve block or standard pain care. Researchers will measure pain scores, opioid consumption, and markers of inflammation in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ropivacaine
What this could lead to
If it works, this could offer a better way to manage pain after mastectomy, reducing the need for opioids and possibly improving recovery.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The nerve block carries rare risks like infection or allergic reaction.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ngoerah Hospital

    Denpasar, Bali, 80113, Indonesia

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