New hope for Hard-to-Treat cancers: first human trial of ERAS-4001 begins

NCT ID NCT07021898

Recruiting now Disease control Sponsor: Erasca, Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 28 times

Summary

This early-stage study tests a new drug called ERAS-4001 in people with advanced solid tumors that have certain KRAS mutations. The main goal is to see if the drug is safe and tolerable when given alone or with other treatments. About 200 participants will take part to help find the right dose and check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Locations

Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
NEXT Oncology
RECRUITING

Irving, Texas, 75039, United States
NEXT Oncology
RECRUITING

San Antonio, Texas, 78229, United States
Sarah Cannon Research Institute (SCRI) Oncology Partners
RECRUITING

Nashville, Tennessee, 32703, United States
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.

METASTATIC SOLID TUMORS