New drug eRapa aims to delay surgery in High-Risk FAP patients
NCT ID NCT06950385
First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 26 times
Summary
This study tests whether the drug eRapa can slow down disease progression in adults with Familial Adenomatous Polyposis (FAP), a condition that causes many polyps in the gut and raises cancer risk. About 168 participants will take eRapa or a placebo daily every other week, with regular check-ups and endoscopies. The goal is to see if eRapa delays serious events like cancer or major surgery, and to check its safety.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam UMC
RECRUITINGAmsterdam, Netherlands
Contact Email: •••••@•••••
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Benaroya Research Institute at Virginia Mason
RECRUITINGSeattle, Washington, 98101, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope
NOT_YET_RECRUITINGArcadia, California, 91007, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic Florida
RECRUITINGWeston, Florida, 33331, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Copenhagen University Hospital
RECRUITINGCopenhagen, Denmark
Contact Email: •••••@•••••
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Dana Farber Cancer Institute
NOT_YET_RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Department of Surgery, Section of Colon Rectal and Surgery
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Digestive & Liver Center of Florida
RECRUITINGOrlando, Florida, 32825, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Geisinger Medical Center
RECRUITINGDanville, Pennsylvania, 17822, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Georgetown University
RECRUITINGWashington D.C., District of Columbia, 20057, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, Spain
Contact Email: •••••@•••••
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Hospital Comarcal de Inca
NOT_YET_RECRUITINGInca, Spain
Contact Email: •••••@•••••
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Hospital La Fe de Valencia
RECRUITINGValencia, Spain
Contact Email: •••••@•••••
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Hospital Oncologico - Puerto Rico Medical Center
RECRUITINGRio Piedras, 00935, Puerto Rico
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21205, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Radboud University Medical Center
RECRUITINGNijmegen, Netherlands
Contact Email: •••••@•••••
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Chicago
NOT_YET_RECRUITINGChicago, Illinois, 60615, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Washington - Fred Hutchinson
RECRUITINGSeattle, Washington, 98195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitätsklinikum Bonn
RECRUITINGBonn, Germany
Contact Email: •••••@•••••
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Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06520, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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