New drug eRapa could slow polyps in inherited colon cancer condition
NCT ID NCT06950385
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if the drug eRapa can slow disease progression in adults with Familial Adenomatous Polyposis (FAP), a condition that causes many polyps in the gut and raises cancer risk. About 168 participants will take eRapa or a placebo daily every other week. Researchers will track how long it takes for the disease to worsen, using colonoscopies and other checks every 3 to 6 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam UMC
RECRUITINGAmsterdam, Netherlands
Contact Email: •••••@•••••
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Benaroya Research Institute at Virginia Mason
RECRUITINGSeattle, Washington, 98101, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope
RECRUITINGArcadia, California, 91007, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic Florida
RECRUITINGWeston, Florida, 33331, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Copenhagen University Hospital
RECRUITINGCopenhagen, Denmark
Contact Email: •••••@•••••
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Department of Surgery, Section of Colon Rectal and Surgery
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Digestive & Liver Center of Florida
RECRUITINGOrlando, Florida, 32825, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Geisinger Medical Center
RECRUITINGDanville, Pennsylvania, 17822, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Georgetown University
RECRUITINGWashington D.C., District of Columbia, 20057, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, Spain
Contact Email: •••••@•••••
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Hospital Comarcal de Inca
RECRUITINGInca, Spain
Contact Email: •••••@•••••
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Hospital General Universitario Gregorio Marañón
RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital La Fe de Valencia
RECRUITINGValencia, Spain
Contact Email: •••••@•••••
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Hospital Oncologico - Puerto Rico Medical Center
RECRUITINGRio Piedras, 00935, Puerto Rico
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Ospedale San Raffaele
RECRUITINGMilan, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Istituto Nazionale dei Tumori
RECRUITINGMilan, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21205, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Radboud University Medical Center
RECRUITINGNijmegen, Netherlands
Contact Email: •••••@•••••
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Chicago
RECRUITINGChicago, Illinois, 60615, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Washington - Fred Hutchinson
RECRUITINGSeattle, Washington, 98195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitätsklinikum Bonn
RECRUITINGBonn, Germany
Contact Email: •••••@•••••
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Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06520, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••