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Could a diet and exercise program help childhood leukemia survivors live healthier?

NCT ID NCT02244411

Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether a personalized diet and exercise program, delivered by phone and online, can help adult survivors of childhood leukemia who are overweight or obese lose weight. Participants are randomly assigned to either the active coaching program or a self-directed approach with standard health guidelines. The study lasts two years and compares weight loss between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a phone- and web-based diet and exercise counseling program
What this could lead to
If successful, this could point toward a practical, scalable way to help childhood leukemia survivors manage weight and reduce long-term health risks.
What could go wrong
This is a behavioral intervention, not a drug, so results may vary widely. Weight loss can be hard to sustain, and the study relies on self-reported data, which may affect accuracy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

358 people

The number who actually took part.

Started

Sep 2014

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Eligibility will be confirmed via the CCSS-based medical record and by a series of questions on the EQUAL website, prior to consent. * Participation in the CCSS cohort * Diagnosed with acute lymphoblastic leukemia \< 18 years of age * Cancer free at time of study enrollment * Current age ≥ 18 years * A body mass index (BMI) ≥ 25 kg/m2 (overweight or obese), as determined by self-reported height and weight on the most recent CCSS questionnaire * Internet access and a personal email account * Able to read and comprehend informed consent Exclusion Criteria: * Prior history of congestive heart failure, coronary artery disease, myocardial infarction, stroke, or unstable angina; * Medical condition for which weight loss might be contraindicated or which would cause weight loss, such as pregnancy, anorexia or bulimia; * Use of prescription weight loss medication within the previous 6 months * History of total body irradiation (TBI)

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adult survivors of childhood leukemia

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, United States

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