Promising combo for Hard-to-Treat prostate cancer hits roadblock

NCT ID NCT02555189

First seen Apr 23, 2026 · Last updated May 13, 2026 · Updated 3 times

Summary

This study looked at adding a drug called ribociclib to standard hormone therapy (enzalutamide) for men with advanced prostate cancer that had spread and stopped responding to hormone treatment. The goal was to find a safe dose and see if the combination could lower PSA levels. The trial was stopped early, so results are limited.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.