New combo therapy shows promise for Tough-to-Treat prostate cancer

NCT ID NCT03674814

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 21 times

Summary

This early-stage study tested a new drug combination for men with advanced prostate cancer that no longer responds to standard hormone therapy. The trial included 42 participants and aimed to see if adding relacorilant to enzalutamide is safe and can help control the disease. Researchers measured side effects, drug levels, and signs of anti-cancer activity like PSA levels and tumor shrinkage.

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Contacts and locations

Locations

  • University Of Chicago Medicine Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.