New combo therapy for tough prostate cancer shows promise in early trial

NCT ID NCT03674814

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested a new combination of two drugs—enzalutamide and relacorilant—in 42 men with advanced prostate cancer that no longer responds to standard hormone therapy. The main goals were to check safety and see how the drugs interact in the body. Researchers also looked for signs that the combination might slow cancer growth.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Of Chicago Medicine Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States