New hope for toddlers with rare brain tumors: targeted pill shrinks cancers without harsh chemo
NCT ID NCT06528691
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 25 times
Summary
This study tests a daily pill called entrectinib for children under 3 with certain types of brain or spinal cord tumors. The drug targets specific gene changes (NTRK or ROS1) to shrink tumors and delay growth. About 52 children will take part, and doctors will measure how well the tumor responds and how long it stays under control.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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GRAACC Hospital (Grupo de Apoio ao Adolescente e à Criança com Câncer)
RECRUITINGSão Paulo, 04039-001, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital Santa Marcelina
RECRUITINGSão Paulo, 08270-070, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital de Câncer de Barretos
RECRUITINGBarretos, São Paulo, 14784400, Brazil
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Instituto Nacional de Enfermedades Neoplásicas
RECRUITINGLima, Peru
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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King Hussein Cancer Center
RECRUITINGAmman, 11941, Jordan
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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