Could a feeding tube after transplant save the gut?

NCT ID NCT07315165

Not yet recruiting Disease control Sponsor: University of Nebraska Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests whether starting tube feeding right after a stem cell transplant can reduce severe gut graft-versus-host disease (GVHD) in people with blood cancers or disorders. About 112 participants will be randomly assigned to either standard care or early tube feeding. The main goal is to see if early nutrition lowers the risk of serious gut GVHD within the first 100 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: enteral nutrition (blenderized tube feed formula)
What this could lead to: If it works, this could show that early tube feeding lowers the risk of severe gut complications after a stem cell transplant.
What could go wrong: This is a small, early-phase trial (112 people) testing a dietary intervention, so results may not be definitive or apply to all patients. Tube feeding can cause discomfort or complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hematologic disorder hematopoietic and lymphoid cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANT (ALLO-HSCT)

Contacts and locations

Locations

Fred & Pamela Buffet Cancer Center

Omaha, Nebraska, 68198, United States

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