Cure My Disease

Don't miss your cure!

 Log in / Sign up

New hope for endometriosis pain: hormone pill targets inflammation

NCT ID NCT07100782

Recruiting now Disease control Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a daily pill called Relugolix CT (Myfembree) can reduce pelvic pain, inflammation, and pain sensitivity in women with endometriosis. Researchers will measure changes in blood markers of inflammation and brain scans related to pain. The trial involves 130 women with moderate-to-severe endometriosis-related pelvic pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Relugolix combination therapy (Relugolix CT, also known as Myfembree) - a pill containing relugolix, estradiol, and norethindrone acetate
What this could lead to
If successful, this could show that hormone suppression with Relugolix CT effectively reduces pelvic pain and inflammation in endometriosis, offering a non-surgical treatment option.
What could go wrong
This is a Phase 3 trial, but it is still early to know if the drug will work for all participants. Side effects from hormone suppression may occur, and the study focuses on specific biomarkers, not just pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ENDOMETRIOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

endometriosis Pelvic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIOSIS PELVIC PAIN

Contacts and locations

Locations

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.