New hope for endometriosis pain: hormone pill targets inflammation
NCT ID NCT07100782
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a daily pill called Relugolix CT (Myfembree) can reduce pelvic pain, inflammation, and pain sensitivity in women with endometriosis. Researchers will measure changes in blood markers of inflammation and brain scans related to pain. The trial involves 130 women with moderate-to-severe endometriosis-related pelvic pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Relugolix combination therapy (Relugolix CT, also known as Myfembree) - a pill containing relugolix, estradiol, and norethindrone acetate
What this could lead to
If successful, this could show that hormone suppression with Relugolix CT effectively reduces pelvic pain and inflammation in endometriosis, offering a non-surgical treatment option.
What could go wrong
This is a Phase 3 trial, but it is still early to know if the drug will work for all participants. Side effects from hormone suppression may occur, and the study focuses on specific biomarkers, not just pain relief.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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