Hormone pills may replace surgery for some older breast cancer patients

NCT ID NCT02476786

Recruiting now Disease control Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether using only hormone-blocking drugs can control breast cancer in women aged 70 and older who have a low-risk, hormone-sensitive tumor. Participants receive standard endocrine therapy instead of surgery or radiation. The goal is to see if this gentler approach is safe and effective for this specific group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: endocrine therapy drugs (goserelin, anastrozole, exemestane, fulvestrant, tamoxifen)
What this could lead to: If successful, this could offer a less invasive treatment option for older women with low-risk breast cancer, potentially avoiding surgery and radiation.
What could go wrong: This is a small, early-phase trial. Endocrine therapy alone may not control the cancer as well as standard treatments, and long-term outcomes are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm estrogen-receptor positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER BREAST NEOPLASMS CANCER OF BREAST CANCER OF THE BREAST

Contacts and locations

Locations

Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.