Gene therapy trial aims to tame severe seizures in young children

NCT ID NCT05419492

First seen Feb 28, 2026 · Last updated May 10, 2026 · Updated 10 times

Summary

This study tests a gene therapy called ETX101 in infants and children with Dravet syndrome, a severe form of epilepsy caused by a genetic change. The treatment uses a harmless virus to deliver a working copy of the gene to help control seizures. The trial will include up to 47 participants and will measure how well the therapy reduces seizure frequency and improves development over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Boston Children's Hospital

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Colorado Children's Hospital

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cook Children's Medical Center

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Great Ormond Street Hospital

    NOT_YET_RECRUITING

    London, WC1N3JH, United Kingdom

    Contact Email: •••••@•••••

  • Nicklaus Children's Hospital

    RECRUITING

    Miami, Florida, 33155, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Science University (OSHU)

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

  • Queen Elizabeth Hospital

    NOT_YET_RECRUITING

    Glasgow, G51 4TF, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Royal Children's Hospital

    RECRUITING

    Melbourne, Australia

    Contact

    Contact

  • UCSF Benioff Children's Hospitals

    RECRUITING

    San Francisco, California, 94158, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.