Could a repurposed drug tame seizures in adult dravet patients?
NCT ID NCT05560282
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested the drug fenfluramine (FINTEPLA) in adults with Dravet syndrome whose seizures were not controlled by other medications. The trial was open-label and added fenfluramine to existing treatments. It aimed to see if the drug could reduce monthly seizures by at least 50%. However, the study was terminated early with only 7 participants enrolled, so results are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fenfluramine (FINTEPLA)
What this could lead to
If it works, this could provide a new treatment option to reduce seizures in adults with Dravet syndrome who don't respond to current medications.
What could go wrong
This small, early-phase trial was terminated, so results are limited. Fenfluramine may cause side effects like appetite loss or heart valve issues, and its benefits in adults are not yet proven.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Toronto Western Hospital
Toronto, Ontario, M5T 2S8, Canada