Could a diabetes drug help hearts stiffened by amyloid?
NCT ID NCT07240844
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether Enavogliflozin, a drug used for diabetes, can help people with amyloid cardiomyopathy, a condition where abnormal proteins build up in the heart. About 68 adults with heart failure symptoms will take the drug or a placebo for 12 weeks, then switch. The main goal is to see if the drug improves heart-related symptoms and daily function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Enavogliflozin
What this could lead to
If it works, this could offer a new treatment option to improve heart function and quality of life in people with amyloid cardiomyopathy.
What could go wrong
This is a small, early-phase trial with only 68 participants. The drug may not show significant benefit over placebo, and side effects are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Samsung Medical Center
RECRUITINGSeoul, 06351, South Korea
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Seoul St. Mary's Hospital, The Catholic University of Korea
RECRUITINGSeoul, 06591, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact