Brain scans reveal why some dementia patients lack Self-Awareness

NCT ID NCT06794580

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 77 people with Alzheimer's or frontotemporal dementia to understand why some lose awareness of their condition (anosognosia). Researchers used EEG and brain scans to measure how the brain responds to mistakes and emotional signals. The goal is to find brain markers that could one day help develop tools to improve self-awareness in early dementia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward new ways to detect and improve self-awareness in early dementia, possibly leading to brain-training tools.
What could go wrong: This is a small, completed observational study, not a treatment trial. The findings may not lead to practical therapies, and any future applications are uncertain.

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Conditions

The condition(s) this trial relates to.

agnosia Alzheimer disease anosognosia behavioral variant of frontotemporal dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANOSOGNOSIA

Contacts and locations

Locations

Institut de la Mémoire et de la Maladie d'Alzheimer (IM2A)

Paris, Paris, 75013, France

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