New drug eltrekibart aims to tame painful skin condition
NCT ID NCT06046729
First seen Jun 25, 2026 · Last updated Jul 08, 2026 · Updated 3 times
Summary
This study tests a new drug called eltrekibart in 352 adults with moderate-to-severe hidradenitis suppurativa (HS), a painful skin condition causing abscesses and inflammation. Participants receive either the drug or a placebo for about 62 weeks. The goal is to find a safe and effective dose that reduces abscesses and pain, offering a potential new option for those who haven't improved with antibiotics.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- eltrekibart (a drug given as an injection under the skin)
- What this could lead to
- If it works, this could point toward a new treatment option for people with moderate-to-severe hidradenitis suppurativa who haven't responded well to antibiotics.
- What could go wrong
- This is an early Phase 2b trial, so the drug may not prove effective or safe enough for wider use. The results are still uncertain, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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ActivMed Practices & Research, Inc.
Portsmouth, New Hampshire, 03801, United States
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Advanced Medical Research, PC
Sandy Springs, Georgia, 30328, United States
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Advanced Research Experts
Nashville, Tennessee, 37211, United States
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Alberta Dermasurgery Centre
Edmonton, Alberta, T6G 1C3, Canada
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Alfred Hospital
Melbourne, Victoria, 3004, Australia
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Alliance Clinical Research of Tampa
Tampa, Florida, 33615, United States
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Apex Clinical Research Center
Mayfield Heights, Ohio, 44124, United States
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Arkansas Research Trials, LLC
North Little Rock, Arkansas, 72117, United States
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Beacon Dermatology
Calgary, Alberta, T3E 0B2, Canada
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Brunswick Dermatology Center
Fredericton, New Brunswick, E3B 1G9, Canada
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Care Access-Marriottsville
Marriottsville, Maryland, 21104, United States
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Center For Dermatology Clinical Research, Inc.
Fremont, California, 94538, United States
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Center de Recherche St Louis
Québec, Quebec, G1W 4R4, Canada
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Centrum Medyczne Pratia Katowice
Katowice, Silesian Voivodeship, 40-081, Poland
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Cityclinic Przychodnia Lekarsko Psychologiczna Matusiak Spółka Partnerska
Wroclaw, Lower Silesian Voivodeship, 50-566, Poland
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Columbia Dermatology & Aesthetics
Columbia, South Carolina, 29212-8623, United States
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Darst Dermatology
Charlotte, North Carolina, 28277-8014, United States
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Dawes Fretzin Clinical Research Group, LLC
Indianapolis, Indiana, 46250, United States
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Derm Research LLC
Louisville, Kentucky, 40217, United States
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DermDox Centers for Dermatology
Camp Hill, Pennsylvania, 17011, United States
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DermDox Dermatology Centers
Sugarloaf, Pennsylvania, 18249, United States
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DermEffects - Probity - PPDS
London, Ontario, N6H 5L5, Canada
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Dermatology Institute and Skin Care Center
Santa Monica, California, 90404, United States
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Dermatology Research Associates
Los Angeles, California, 90045, United States
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Dermatology Specialists of Charlotte
Charlotte, North Carolina, 28277, United States
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Dermatology Specialists of Spokane
Spokane, Washington, 99202-1332, United States
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Dermoklinika-Centrum Medyczne s.c
Lodz, Łódź Voivodeship, 90-436, Poland
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Direct Helpers Research Center
Hialeah, Florida, 33012, United States
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Duke University Medical Center
Durham, North Carolina, 27710-3038, United States
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East Sydney Doctors
Darlinghurst, New South Wales, 2010, Australia
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Equity Medical - Bowling Green
Bowling Green, Kentucky, 42104, United States
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First OC Dermatology Research Inc
Fountain Valley, California, 92708, United States
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ForCare Clinical Research
Tampa, Florida, 33613-1244, United States
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Fremantle Dermatology
Fremantle, Western Australia, 6160, Australia
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Hautarztpraxis Mahlow
Blankenfelde-Mahlow, Brandenburg, 15827, Germany
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Hautklinik Erlangen
Erlangen, Bavaria, 91054, Germany
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Hautzentrum Friedrichshain - Dermatologie
Berlin, 10247, Germany
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Holdsworth House Medical Practice
Sydney, 2010, Australia
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Hospital of Venereal and Skin Diseases A.Syggros
Athens, Attica, 16121, Greece
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International Clinical Research - Tennessee (IC Research)
Murfreesboro, Tennessee, 37130, United States
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Jordan Valley Dermatology Center
South Jordan, Utah, 84095, United States
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Klinika Badawcza Centrum Badan Klinicznych Wojciech Brzezicki
Malbork, Pomeranian Voivodeship, 82-200, Poland
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Medical Dermatology Specialists
Phoenix, Arizona, 85006, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Modern Research Associates
Dallas, Texas, 75231, United States
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North Texas Clinical Research
Frisco, Texas, 75034, United States
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NorthShore Medical Group Dermatology - Skokie
Skokie, Illinois, 60077-1049, United States
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Northwest Arkansas Clinical Trials Center
Rogers, Arkansas, 72758, United States
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Olympian Clinical Research
Tampa, Florida, 33615, United States
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Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych i Administracji
Warsaw, Masovian Voivodeship, 02-507, Poland
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Papageorgiou General Hospital of Thessaloniki
Thessaloniki, Thessaloníki, 56429, Greece
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Revival Research Institute - Troy
Troy, Michigan, 48084, United States
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Saguaro Dermatology Associates, LLC - Probity - PPDS
Phoenix, Arizona, 85008, United States
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Simcoderm Medical & Surgical Dermatology Centre
Barrie, Ontario, L4M 7G1, Canada
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Sinclair Dermatology - East Melbourne
East Melbourne, Victoria, 3002, Australia
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Skin Research of South Florida
Miami, Florida, 33173-1407, United States
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Skin Specialists, P.C
Omaha, Nebraska, 68144, United States
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Sunshine Coast University Hospital
Birtinya, Queensland, 4575, Australia
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Universitaetsklinikum Hamburg-Eppendorf
Hamburg, 20251, Germany
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Universitaetsklinikum der Ruhr-Universitaet Bochum (UKRUB) - St. Josef-Hospital
Bochum, North Rhine-Westphalia, 44791, Germany
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University General Hospital of Heraklion Loc. 1
Heraklion, Irakleío, 711 10, Greece
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Connecticut
Farmington, Connecticut, 06032, United States
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University of Miami
Miami, Florida, 33125, United States
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Universitätsklinikum Bonn
Bonn, North Rhine-Westphalia, 53127, Germany
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Universitätsklinikum Frankfurt
Frankfurt am Main, Hesse, 60596, Germany
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Universitätsklinikum Münster - Albert Schweitzer Campus
Münster, Westfalen, 48149, Germany
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Uniwersyteckie Centrum Kliniczne
Gdansk, Pomeranian Voivodeship, 80-214, Poland
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Westmead Hospital
Westmead, New South Wales, 2145, Australia
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Wiseman Dermatology Research Inc.
Winnipeg, Manitoba, R3M 3Z4, Canada
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Wro Medica
Wroclaw, Lower Silesian Voivodeship, 51-685, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Head-to-Head: which pill tames hidradenitis suppurativa best?
- Skin disease evolution under the microscope: a 17-Year look at what drives severity
- Could early treatment tame a painful skin condition?
- New pill shows promise for controlling painful skin condition in long-term trial
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- New pill for painful skin disease enters first human tests