Experimental pill combo for High-Risk MDS shows early promise but trial halted

NCT ID NCT05918055

First seen Jan 11, 2026 · Last updated Apr 24, 2026 · Updated 16 times

Summary

This study tested two oral drugs, eltanexor and Inqovi, in adults with high-risk myelodysplastic syndromes (MDS) that did not improve with standard treatment. The goal was to find the best dose and see if the combination could control the disease. Only 3 people enrolled before the trial was stopped early. Participants took the pills at home in 28-day cycles and were monitored for side effects and response.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.