New drug cocktail aims to wipe out myeloma cells in newly diagnosed patients

NCT ID NCT06997081

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests whether combining elranatamab (an immune-boosting drug) with lenalidomide and dexamethasone can eliminate all traces of multiple myeloma in newly diagnosed patients. About 104 participants will receive the drugs in cycles over several months. The main goal is to see if the cancer becomes undetectable in bone marrow after 12 cycles.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Elranatamab, lenalidomide, and dexamethasone

What this could lead to

If successful, this combination could help more newly diagnosed myeloma patients achieve deep remission with no detectable cancer cells.

What could go wrong

This is an early Phase 2 study with only 104 participants. The treatment may cause side effects like immune reactions or infections, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact