Stockings or not? major trial tests if blood thinners alone prevent clots after joint replacement.

NCT ID NCT06563531

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether patients recovering from hip or knee replacement can safely skip elastic compression stockings and rely only on blood-thinning drugs to prevent dangerous blood clots. Over 1,200 participants will be randomly assigned to receive either drugs plus stockings or drugs alone, and followed for 90 days. The goal is to see if the drug-only approach is just as effective at preventing clots and pulmonary embolism.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pharmacological thromboprophylaxis (blood-thinning drugs)

What this could lead to

If successful, this could simplify recovery after hip or knee replacement by removing the need for uncomfortable compression stockings.

What could go wrong

This is an early-stage study comparing two prevention methods; it may find that skipping stockings increases clot risk, so results are not yet practice-changing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism prevention target thrombophilia due to thrombin defect prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinique Pasteur Lanroze

    RECRUITING

    Brest, 29000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••