Scientists hunt for clues to rare immune disease
NCT ID NCT00315380
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 700 people with eosinophilic granulomatosis with polyangiitis (EGPA), a rare immune disorder causing asthma, high eosinophil levels, and blood vessel inflammation. Researchers aim to discover biological markers that can measure disease activity and predict treatment response. No new treatments are tested; the goal is to better understand and monitor the disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AOU Meyer IRCCS
RECRUITINGFlorence, Italy
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Brigham and Women's Hospital
COMPLETEDBoston, Massachusetts, 02215, United States
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Cleveland Clinic Foundation
COMPLETEDCleveland, Ohio, 44195, United States
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Imperial College Healthcare NHS Trust/ Imperial College London
RECRUITINGLondon, W12 0NN, United Kingdom
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Mayo Clinic
COMPLETEDRochester, Minnesota, 55905, United States
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Mount Sinai Hospital
COMPLETEDToronto, Ontario, Canada
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National Jewish Health
COMPLETEDDenver, Colorado, 80206, United States
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St. Joseph's Healthcare
RECRUITINGHamilton, Ontario, Canada
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University of California San Diego
COMPLETEDSan Diego, California, 92122, United States
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University of Pennsylvania
COMPLETEDPhiladelphia, Pennsylvania, 19104, United States
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University of Pittsburgh
COMPLETEDPittsburgh, Pennsylvania, 15260, United States
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University of Utah
COMPLETEDSalt Lake City, Utah, 84112, United States
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medius KLINIK KIRCHHEIM
RECRUITINGKirchheim unter Teck, 73230, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New hope for rare disease: can NS-229 help patients reduce steroids?
- New study tracks Nucala's Long-Term impact on rare inflammatory disease
- Scientists build tissue bank to unlock vasculitis mysteries
- New drug aims to tame rare inflammatory disease EGPA
- New drug MT-2990 tested in rare blood vessel disease