New hope for kids with tough cancer: drug may keep neuroblastoma at bay

NCT ID NCT07278674

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug eflornithine, taken as a pill after immunotherapy, can help prevent high-risk neuroblastoma from coming back in children. Twenty children under 18 who have completed standard treatment will take eflornithine for maintenance. Researchers will track how long they stay cancer-free and monitor for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

eflornithine

What this could lead to

If it works, this could help prevent relapse and improve survival in children with high-risk neuroblastoma after standard treatment.

What could go wrong

This is a small, early-phase study with only 20 participants, so results may not apply broadly. Side effects from eflornithine are possible and will be monitored.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuroblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ruijin Hospital Hainan Branch, affiliated with Shanghai Jiao Tong University School of Medicine and Children's Hospital of Shanghai, affiliated with Shanghai Jiao Tong University School of Medicine

    Hainan, China