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New shot could help thyroid patients who Don't respond to usual pills

NCT ID NCT07596849

Recruiting now Disease control Sponsor: argenx Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study tests an investigational drug called efgartigimod for adults with Graves' disease whose thyroid levels are still high despite taking standard antithyroid medications. About 230 participants will receive either the drug or a placebo as a shot under the skin. The goal is to see if the drug can help bring thyroid hormone levels back to normal and allow patients to reduce or stop their current pills.

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Conditions

The condition(s) this trial relates to.

Graves disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRAVES DISEASE

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Aso Iizuka Hospital

    RECRUITING

    Iizuka, 820-8505, Japan

  • First Medical Clinic Ltd

    RECRUITING

    Tbilisi, 0102, Georgia

  • High Technology Hospital Medcenter LLC

    RECRUITING

    Batumi, 6000, Georgia

  • LTD MediClub Georgia

    RECRUITING

    Tbilisi, 0160, Georgia

  • National Hospital Organization Kyoto Medical Center

    RECRUITING

    Kyoto, 612-0861, Japan

  • SHOWA Medical University Northern Yokohama Hospital

    RECRUITING

    Yokohama, 224-8503, Japan

  • Tottori University Hospital

    RECRUITING

    Yonago, 683-8504, Japan

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