Blood filter during heart bypass may prevent organ damage, but trial stopped early

NCT ID NCT06659289

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a device called Efferon LPS that filters blood during heart surgery when a heart-lung machine is used. The goal was to see if it could prevent multiple organ failure, especially kidney damage. Only 14 people took part before the study was stopped, so the results are not reliable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Efferon LPS hemoperfusion device

What this could lead to

If it works, this device could reduce the risk of organ failure and kidney damage after heart surgery.

What could go wrong

The trial was terminated early with only 14 participants, so results are very limited. It is unclear if the device provides any real benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart disorder acute kidney injury prevention target multiple organ dysfunction syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pavlov First Saint Petersburg State Medical University

    Saint Petersburg, Russia