Liver study tests safety of new drugs in patients with liver disease
NCT ID NCT07546760
First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 4 times
Summary
This early-stage study looks at how the liver handles two experimental drugs, AZD9550 and AZD6234, in people with moderate to severe liver problems compared to healthy volunteers. About 28 adults will receive a single injection of one drug. The goal is to see if liver impairment changes drug levels or safety. No treatment benefit is expected; the focus is purely on safety and drug processing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AZD9550 and AZD6234 (two experimental drugs given as a single injection under the skin)
- What this could lead to
- If successful, this study will help determine safe dosing for people with liver problems, potentially making future treatments safer for them.
- What could go wrong
- This is a very early Phase 1 study with only 28 participants, so results may not apply broadly. The drugs are experimental and their effectiveness is not being tested here.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Research Site
RECRUITINGChandler, Arizona, 85225, United States
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Research Site
RECRUITINGRialto, California, 92377, United States
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Research Site
RECRUITINGMiami Lakes, Florida, 33014, United States
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Research Site
RECRUITINGSan Antonio, Texas, 78215, United States
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Other studies related to the condition(s) this trial covers.
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