New inhaler propellant put to the test in healthy volunteers
NCT ID NCT06506266
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed phase 1 study in 24 healthy adults compared a new inhaler propellant (HFA-152a) to a standard one (HFA-134a) to see if it affects how the lungs clear mucus. Participants inhaled each propellant for several days, and lung clearance was measured using a radioactive tracer. The goal is to ensure the new propellant is safe for use in asthma inhalers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HFA-152a (a propellant used in inhalers)
- What this could lead to
- If HFA-152a is shown to be safe and not harm lung clearance, it could become a more environmentally friendly propellant for asthma inhalers.
- What could go wrong
- This is a very early, small study in healthy people, not those with asthma. It only measures lung clearance, not whether the propellant works for treating asthma. Results may not apply to patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ASTHMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
GSK Investigational Site
Nottingham, NG11 6JS, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- AI and a smartphone app may let kids with asthma skip clinic visits
- Allergy tablets under the tongue may cut hay fever drug use for years, massive real-world study suggests
- Short steroid course after first wheeze may stop asthma before it starts
- New antibody drug aims to tame Hard-to-Control asthma
- New asthma drug aims to improve breathing without daily pills
- Scientists compare two formulations of a potential asthma treatment