Breathing and eye pressure: tiny study explores CO2's role in Kids' vision

NCT ID NCT06275308

Recruiting now Knowledge-focused Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how changing carbon dioxide (CO2) levels in the blood affects eye pressure and the thickness of a layer behind the retina (choroid) in children. Researchers will adjust breathing during eye exams under anesthesia for 20 children aged newborn to 8 years. The goal is to understand the relationship between CO2 and eye pressure, which could help manage conditions like glaucoma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ventilation manipulation (adjusting carbon dioxide levels)
What this could lead to: If successful, this could help doctors understand how breathing and CO2 levels influence eye pressure, potentially improving care for children with eye conditions.
What could go wrong: This is a very small, early study with only 20 children, so results may not apply to everyone. It is purely observational and does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ocular hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRAOCULAR PRESSURE

Contacts and locations

Locations

University of Pittsburgh Medical Center
RECRUITING

Pittsburgh, Pennsylvania, 15224, United States

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