Can a tiny clip seal a heart pouch and prevent strokes?
NCT ID NCT07742839
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This study is testing a device called the ECLIPTIS clip, which is placed during open-heart surgery to close off the left atrial appendage—a small pouch in the heart where blood can pool and form clots that may cause strokes. The trial will enroll about 168 adults who are already scheduled for heart surgery and will check how well the clip seals the pouch and whether it causes any major complications within 30 days. The goal is to see if this clip is a safe and effective way to reduce stroke risk in people with heart conditions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Edwards ECLIPTIS Left Atrial Appendage Exclusion System (a surgical clip)
- What this could lead to
- If successful, this could provide a safe and effective way to close the left atrial appendage during heart surgery, potentially reducing the risk of stroke in patients with atrial fibrillation.
- What could go wrong
- This is an observational study, so it doesn't compare the clip to other treatments. The results depend on the skill of surgeons and may not apply to all patients. There are risks of bleeding, infection, or other complications from the procedure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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