New mRNA vaccine targets Epstein-Barr virus in first human trial
NCT ID NCT07557602
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial is testing a new mRNA vaccine called VXCO-102 against Epstein-Barr virus (EBV) in 45 healthy adults aged 18 to 25. The main goal is to check if the vaccine is safe and triggers an immune response. EBV is a common virus that can cause mononucleosis and is linked to some cancers, so a successful vaccine could have a big impact.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- VXCO-102 (mRNA vaccine targeting Epstein-Barr virus)
- What this could lead to
- If successful, this could pave the way for a vaccine to prevent EBV infection, which is linked to mononucleosis and certain cancers.
- What could go wrong
- This is an early Phase 1 trial with only 45 participants, so it is primarily testing safety, not effectiveness. The vaccine may not produce a strong immune response or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nucleus Network Pty Ltd
Melbourne, Victoria, 3004, Australia
-
Q-Pharm Pty Ltd/Nucleus Network Pty Ltd
Herston, Queensland, 4006, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a nanoparticle vaccine stop the virus behind mono and some cancers?
- Which EBV test is most accurate? study puts three automated assays Head-to-Head
- New drug duo takes on stubborn Epstein-Barr virus
- New EBV vaccines enter human safety trials
- Scientists hunt for genetic clues to severe viral infections