New mRNA vaccine targets Epstein-Barr virus in first human trial

NCT ID NCT07557602

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new mRNA vaccine called VXCO-102 against Epstein-Barr virus (EBV) in 45 healthy adults aged 18 to 25. The main goal is to check if the vaccine is safe and triggers an immune response. EBV is a common virus that can cause mononucleosis and is linked to some cancers, so a successful vaccine could have a big impact.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
VXCO-102 (mRNA vaccine targeting Epstein-Barr virus)
What this could lead to
If successful, this could pave the way for a vaccine to prevent EBV infection, which is linked to mononucleosis and certain cancers.
What could go wrong
This is an early Phase 1 trial with only 45 participants, so it is primarily testing safety, not effectiveness. The vaccine may not produce a strong immune response or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nucleus Network Pty Ltd

    Melbourne, Victoria, 3004, Australia

  • Q-Pharm Pty Ltd/Nucleus Network Pty Ltd

    Herston, Queensland, 4006, Australia

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Other studies related to the condition(s) this trial covers.