Ebola vaccine trial targets HIV-Positive adults and teens

NCT ID NCT03031912

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an experimental Ebola vaccine (V920) in 251 HIV-infected adults and adolescents to see if it is safe and triggers an immune response. Participants received either the vaccine or a placebo, and researchers monitored side effects and antibody levels. The trial took place in Canada and Africa, with results helping to determine if the vaccine can protect people with HIV from Ebola.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

V920 (rVSVΔG-ZEBOV-GP) Ebola virus vaccine

What this could lead to

If successful, this could show that the Ebola vaccine is safe and effective for people living with HIV, expanding protection to a vulnerable group.

What could go wrong

This is a phase 2 trial with 251 participants, so results are still early. The vaccine may not produce a strong immune response in all HIV patients, and side effects like fever or joint pain are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease Ebola hemorrhagic fever prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHUM

    Montreal, Quebec, H2X 0A9, Canada