Blood and AI join forces to catch lung scarring early in rheumatic disease patients
NCT ID NCT07541638
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study aims to find better ways to detect lung scarring (interstitial lung disease) early in people with connective tissue diseases like scleroderma or rheumatoid arthritis. Researchers will analyze tiny particles in the blood called extracellular vesicles and use AI to examine CT scans. They will compare 100 patients with lung scarring to 100 without, tracking them for a year to see if these tools can predict who will get worse.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple blood test that helps doctors spot lung scarring earlier in people with rheumatic diseases.
What could go wrong
This is an observational study, not a treatment trial. It may not find reliable biomarkers, and any test developed would need further validation before use.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione Policlinico Universitario A. Gemelli IRCCS
RECRUITINGRoma, 00168, Italy
Contact Email: •••••@•••••
Contact