New study aims to catch pancreatic cancer sooner in diabetics

NCT ID NCT04662879

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large study is testing whether a risk-scoring tool (called ENDPAC) can identify people with new-onset diabetes who are at higher risk for pancreatic cancer. About 8,800 participants aged 50-85 will have their medical records checked for age, weight changes, and blood sugar trends. Those flagged as high risk will get a CT or MRI scan to look for early signs of pancreatic cancer. The goal is to see if this approach can detect the cancer earlier than usual.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a screening method that catches pancreatic cancer earlier in people with new-onset diabetes, potentially improving survival.

What could go wrong

This is an observational study, not a treatment trial. The algorithm may not prove accurate enough for widespread use, and early detection does not guarantee better outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus hyperglycemia pancreatic ductal adenocarcinoma Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Kaiser Permanente Southern California, Kaiser Permanente Research

    Pasadena, California, 91101, United States