New study aims to catch pancreatic cancer sooner in diabetics

NCT ID NCT04662879

Ongoing Knowledge-focused Sponsor: Pancreatic Cancer Action Network Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large study is testing whether a risk-scoring tool (called ENDPAC) can identify people with new-onset diabetes who are at higher risk for pancreatic cancer. About 8,800 participants aged 50-85 will have their medical records checked for age, weight changes, and blood sugar trends. Those flagged as high risk will get a CT or MRI scan to look for early signs of pancreatic cancer. The goal is to see if this approach can detect the cancer earlier than usual.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a screening method that catches pancreatic cancer earlier in people with new-onset diabetes, potentially improving survival.
What could go wrong: This is an observational study, not a treatment trial. The algorithm may not prove accurate enough for widespread use, and early detection does not guarantee better outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus hyperglycemia pancreatic ductal adenocarcinoma Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS HYPERGLYCEMIA PANCREAS DUCTAL ADENOCARCINOMA

Contacts and locations

Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
Kaiser Permanente Southern California, Kaiser Permanente Research

Pasadena, California, 91101, United States

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