Can early chemo beat the clock against colon cancer?

NCT ID NCT01460589

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether starting chemotherapy 10 to 14 days after surgery for stage III colon cancer is better than waiting the usual 2 weeks or more. About 300 patients are taking part to see if earlier treatment improves survival and lowers the chance of cancer coming back. The trial also checks for side effects and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
FOLFOX chemotherapy (oxaliplatin, leucovorin, 5-FU)
What this could lead to
If early chemotherapy works better, it could become a new standard to reduce cancer recurrence and improve survival for stage III colon cancer patients.
What could go wrong
This is a moderate-sized phase 3 trial, but results may not apply to all patients. Early chemo could increase side effects or complications without clear benefit.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jun Seok Park

    Daegu, South Korea

  • Kyungpook National University Medical center

    Daegu, 41404, South Korea

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