Can a breath test replace scans for lung cancer? new study aims to find out

NCT ID NCT07218601

Recruiting now Diagnosis Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new technology called an electronic nose (E-Nose) that analyzes chemicals in a person's breath. Researchers want to see if it can accurately measure how well lung cancer responds to treatment and if the cancer comes back. The study involves 60 adults with non-small cell lung cancer who will provide breath samples before and after treatment and during follow-up. The E-Nose is completely non-invasive, so there are no physical risks from the test itself.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Electronic nose (E-Nose) breath analysis
What this could lead to: If successful, this could lead to a simple, non-invasive breath test to monitor lung cancer treatment response and detect recurrence early, reducing the need for frequent scans or biopsies.
What could go wrong: This is an early-phase study with only 60 participants, so results may not apply to all patients. The technology is still experimental and may not be accurate enough to replace standard monitoring.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (All Protocol Activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Monmouth (All Protocol Activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (All Protocol Activities)
RECRUITING

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester (All Protocol Activities)
RECRUITING

Harrison, New York, 10604, United States

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