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Scientists probe the mechanics of E-Cigarette withdrawal to find better quit strategies

NCT ID NCT06066996

Recruiting now Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study investigates what happens when exclusive e-cigarette users stop vaping, focusing on withdrawal symptoms like cravings, mood changes, and sleep disruption. Researchers will give participants either a nicotine patch or a placebo patch to see how nicotine affects these symptoms. The goal is to better understand the withdrawal process and identify targets for future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transdermal nicotine patch or placebo patch
What this could lead to
If successful, this research could identify specific targets for helping people quit e-cigarettes by managing withdrawal symptoms.
What could go wrong
This is an early-phase study focused on understanding withdrawal, not testing a treatment. Results may not lead to practical interventions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

substance withdrawal syndrome Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

E-CIGARETTE USE WITHDRAWAL

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Behavioral Pharmacology Research Unit

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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