Tiny study probes urea breakdown in dialysis patients
NCT ID NCT05076318
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study from Aarhus University looked at how the urea cycle works in 10 people with end-stage kidney disease on dialysis. Participants received a 3-hour alanine infusion, and researchers measured urea production before and after dialysis. The goal was to understand urea cycle dysregulation, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- alanine infusion
- What this could lead to
- If successful, this could improve understanding of urea cycle problems in kidney failure, potentially guiding better dialysis or dietary management.
- What could go wrong
- This is a very small, early-stage observational study with only 10 participants, so results may not apply broadly. It is not testing a treatment, only measuring a biological process.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital Aarhus
Aarhus N, 8200, Denmark
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