Can a shot help kids with eczema sleep through the night?

NCT ID NCT05042258

Recruiting now Symptom relief Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether dupilumab (Dupixent) can improve sleep and reduce itching in 40 children aged 6-17 with moderate to severe eczema. Participants receive dupilumab for 12 weeks, and researchers measure sleep quality and itch using questionnaires and overnight sleep tests. The goal is to see if treating the skin condition also helps kids sleep better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dupilumab (Dupixent)
What this could lead to: If successful, this could show that dupilumab helps children with eczema sleep better and itch less, improving their daily life.
What could go wrong: This is a small, early-phase study with no placebo group, so results may not be definitive. It also only looks at short-term effects over 12 weeks.

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Conditions

The condition(s) this trial relates to.

atopic eczema Parasomnias sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS SLEEP DISTURBANCE

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Lurie Children's Hospital/Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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