Which pill works better for chronic pain? study pits duloxetine against desipramine

NCT ID NCT03548454

First seen Nov 06, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tested two antidepressant medications, duloxetine and desipramine, to see which one is more effective at reducing pain in people with chronic pain. 86 adults with pain lasting more than 3 months were randomly assigned to one of the two drugs. The main goal was to see how many people in each group had at least a 30% drop in pain intensity over six months.

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Contacts and locations

Locations

  • Stanford Pain Management Center

    Redwood City, California, 94063, United States

Conditions

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