Could brain cell implants ease Parkinson's? new trial begins

NCT ID NCT06753331

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a cell therapy called DSP-1083, implanted directly into the brain, for people with Parkinson's disease. About 25 participants will either get the real implant or a sham surgery to see if it's safe and helps control symptoms. The goal is to replace damaged cells that produce dopamine, a chemical lost in Parkinson's.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DSP-1083 (a cell therapy implanted into the brain)

What this could lead to

If it works, this could point toward a new way to control Parkinson's symptoms by replacing damaged brain cells, potentially reducing the need for medication.

What could go wrong

This is an early Phase 1/2 trial with only 25 people, so it's mainly checking safety. The surgery carries risks like infection or brain swelling, and the cells may not work or could cause abnormal growth.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • New York Presbyterian Hospital-Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Kentucky Medical Center

    RECRUITING

    Lexington, Kentucky, 40536, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••