Could brain cell implants ease Parkinson's? new trial begins
NCT ID NCT06753331
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests a cell therapy called DSP-1083, implanted directly into the brain, for people with Parkinson's disease. About 25 participants will either get the real implant or a sham surgery to see if it's safe and helps control symptoms. The goal is to replace damaged cells that produce dopamine, a chemical lost in Parkinson's.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- DSP-1083 (a cell therapy implanted into the brain)
- What this could lead to
- If it works, this could point toward a new way to control Parkinson's symptoms by replacing damaged brain cells, potentially reducing the need for medication.
- What could go wrong
- This is an early Phase 1/2 trial with only 25 people, so it's mainly checking safety. The surgery carries risks like infection or brain swelling, and the cells may not work or could cause abnormal growth.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON'S DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
New York Presbyterian Hospital-Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
-
University of Kentucky Medical Center
RECRUITINGLexington, Kentucky, 40536, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- High-Resolution brain scans aim to unmask Tau's role in Parkinson's
- Can brain stimulation sharpen Decision-Making in Parkinson's?
- Can Stem-Cell implants restore movement in Parkinson's?
- Wild blueberries put to the test for Parkinson's motor symptoms
- Could tailored brain stimulation quiet Parkinson's tremors more effectively?
- Zapping away tremors: scientists probe how electrical stimulation calms shaky hands