New hope for kids with down syndrome and leukemia: asia-wide study tests tailored chemo

NCT ID NCT03286634

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a chemotherapy plan specially designed for children with Down syndrome who have a new diagnosis of acute lymphoblastic leukemia (ALL). The treatment uses lower doses of certain drugs to reduce side effects while still fighting the cancer. About 60 children across Asia are taking part, and researchers will track how many stay cancer-free for 5 years.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chang Gung Memorial Hopsital, Linkou

    Taoyuan, 333, Taiwan

  • KK Women's and Children's Hospital

    Singapore, 229899, Singapore

  • Kagoshima University Hospital

    Kagoshima, 890-8544, Japan

  • Mackay Memorial Hospital

    Taipei, 10449, Taiwan

  • National Taiwan University Children's Hospital

    Taipei, 100, Taiwan

  • National University Hospital

    Singapore, 119074, Singapore

  • Prince of Wales Hospital

    Shatin, New Territories, Hong Kong

  • Siriraj Hospital Mahidol University

    Bangkok, 10700, Thailand

  • Subang Jaya Medical Centre

    Subang Jaya, 47500, Malaysia

  • University of Malaya Medical Centre

    Kuala Lumpur, 59100, Malaysia

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Other studies related to the condition(s) this trial covers.