Can a Cannabis-Like drug cut opioid use after knee surgery?

NCT ID NCT04734080

First seen Apr 02, 2026 · Last updated May 13, 2026 · Updated 8 times

Summary

This study tested whether dronabinol, a drug similar to cannabis, can help reduce the need for strong painkillers (opioids) after knee replacement surgery. 114 adults scheduled for knee replacement took either dronabinol or a placebo before and after surgery. Researchers measured opioid use, pain levels, and recovery time to see if dronabinol made a difference.

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Contacts and locations

Locations

  • Hospital for Special Surgery

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.