Can a simple breathing machine tweak save lungs during surgery?

NCT ID NCT03884543

First seen Nov 19, 2025 · Last updated Apr 28, 2026 · Updated 23 times

Summary

This study tested whether using a personalized breathing machine setting during open abdominal surgery could prevent lung complications like pneumonia or respiratory failure. Over 1,400 adults at risk for lung problems took part. The approach aimed to avoid high pressure on the lungs while under anesthesia.

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Contacts and locations

Locations

  • Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

    Amsterdam, Netherlands

  • Albert Schweitzer Ziekenhuis

    Dordrecht, Netherlands

  • Amsterdam UMC location VUmc

    Amsterdam, Netherlands

  • Bermanntrost BG Klinikum Halle

    Halle, Germany

  • Bernhoven Hospital

    Uden, Netherlands

  • Erasmus Medisch Centrum

    Rotterdam, Netherlands

  • HAGA

    The Hague, Netherlands

  • Haaglanden Medisch Centrum

    The Hague, Netherlands

  • Heinrich-Heine University Hospital Dusseldorf

    Düsseldorf, Germany

  • Leiden UMC

    Leiden, Netherlands

  • Maastricht UMC

    Maastricht, Netherlands

  • Martini Hospital

    Groningen, Netherlands

  • Medical Center Leeuwarden

    Leeuwarden, Netherlands

  • Noordwest ziekenhuizengroep Alkmaar

    Alkmaar, Netherlands

  • Onze Lieve Vrouwen Gasthuis

    Amsterdam, Netherlands

  • Ospedale Policlinico San Martino

    Genoa, Italy

  • Radboud UMC

    Nijmegen, Netherlands

  • Rijnstate Hospital

    Arnhem, Netherlands

  • Spaarne Gasthuis Hospital

    Haarlem, Netherlands

  • UMC Groningen

    Groningen, Netherlands

  • University hospital Carl Gustav Carus

    Dresden, Germany

  • University hospital Napoli

    Naples, Italy

Conditions

Explore the condition pages connected to this study.