Gene-Targeted screening could revolutionize prostate cancer detection

NCT ID NCT07265414

First seen Jan 05, 2026 · Last updated May 13, 2026 · Updated 22 times

Summary

This study looks at whether a new screening method using PHI blood test and mp-MRI scans can find prostate cancer earlier in men with DNA repair gene (DRG) mutations. Current screening often misses aggressive cancers in these men. The goal is to catch more cancers early, when they are easier to treat, while avoiding unnecessary tests in low-risk men. About 320 men with or at risk for prostate cancer will take part.

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Contacts and locations

Locations

  • IRCCS Humanitas Research Hospital

    Milan, 20089, Italy

Conditions

Explore the condition pages connected to this study.