New drug combo aims to tackle Hard-to-Treat myeloma

NCT ID NCT07217119

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study is testing a combination of two drugs, belantamab mafodotin and feladilimab, in 25 people with relapsed/refractory multiple myeloma who have already tried at least three other treatments. The main goal is to check the safety of the combination and find the best dose to use in future studies. Researchers will also look at how well the drugs shrink the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

belantamab mafodotin and feladilimab

What this could lead to

If this combination proves safe and effective, it could offer a new treatment option for people with multiple myeloma that has stopped responding to other therapies.

What could go wrong

This is a very early, small trial (25 people) focused on safety and dosing, not on proving the combination works. Side effects, including eye problems and blood issues, are possible. Many early-stage cancer drug combinations do not advance to become standard treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    Atlanta, Georgia, 30322, United States

  • GSK Investigational Site

    Madison, Wisconsin, 53792, United States

  • GSK Investigational Site

    Fitzroy, Victoria, 3065, Australia

  • GSK Investigational Site

    Melbourne, Victoria, 3000, Australia

  • GSK Investigational Site

    Vancouver, British Columbia, V5Z1M9, Canada

  • GSK Investigational Site

    Toronto, Ontario, M5G2M9, Canada

  • GSK Investigational Site

    Villejuif, 94805, France

  • GSK Investigational Site

    Hamburg, 22083, Germany

  • GSK Investigational Site

    Utrecht, 3584CX, Netherlands

  • GSK Investigational Site

    Pamplona Navarra, 31008, Spain

  • GSK Investigational Site

    Stockholm, SE-141 86, Sweden