New hope for AL amyloidosis patients who failed first-line therapy
NCT ID NCT04270175
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding daratumumab back to pomalidomide and dexamethasone can improve complete remission rates in 15 adults with relapsed or refractory AL amyloidosis who have already received daratumumab. Participants receive the three-drug combination to control the disease. The goal is to see if this approach works better than pomalidomide and dexamethasone alone.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston University Medical Center
Boston, Massachusetts, 02118, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Stanford University
Palo Alto, California, 94304, United States
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Weill Cornell Medicine - Multiple Myeloma Center
New York, New York, 10065, United States